Effect of agitation and aggression on quality of life in patients with dementia

Background Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in patients with during the course disease. Among BPSD symptoms, agitation aggression a source distress for both their caregivers. In this study, we investigated impact on Quality Life (QoL) living long-term care homes or admitted to psychiatric inpatient units. Method Data were obtained from Standardizing Care Neuropsychiatric Symptoms Dementia (StaN) multisite trial conducted Canada. Agitation assessed Cohen-Mansfield Inventory (CMAI) Clinician rating scale (NPI-C); QoL informant-rated Alzheimer’s Disease Related (ADRQL) tool; stage Functional Assessment Staging Tool (FAST); burden physical illness Cumulative Illness Rating Scale-Geriatric (CIRS-G). Regressions performed investigate associations between controlling demographic factors, FAST score, CIRS-G score. Result 179 participants included (52.5% female; mean (SD) age = 80.79 (9.45) years. The ADRQL score was correlated with: (1) CMAI total frequency (Pearson’s r -.333, p<.001); (2) NPI-C -.209, p .005); (3) -.300, p<.001). remained significant (β -.235, SE B 0.054, p<.001), composite -.288, 1.254, p<.001) after age, sex, current residence, Conclusion is related dementia. relationship independent dementia, comorbid illness. This suggests that better management may be an important factor improving